Dennd6b | DENN domain containing 6B

GeneMGI:1916690Synonyms: 1700027J05Rik, Fam116b

Physiological systems

20 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hearing/vestibular/ear Behavior/neurological

17 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating lipase level1 supporting datasetDennd6bem1(IMPC)HmguhomozygoteEarly adult1.88x10-5 
abnormal auditory brainstem response1 supporting datasetDennd6bem1(IMPC)JhomozygoteEarly adult3.2x10-5 
decreased locomotor activity1 supporting datasetDennd6bem1(IMPC)JhomozygoteEarly adult4.72x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dennd6bem1(IMPC)HmguExon Deletionmouse
Dennd6bem1(IMPC)JExon Deletionmouse
Dennd6btm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Dennd6btm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Dennd6btm84005(L1L2_Pgk_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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