1700025G04Rik | RIKEN cDNA 1700025G04 gene
GeneMGI:1916649
Physiological systems
17 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological
11 No significant impact
7 Not tested
Data collections
Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
enlarged lymph nodes | 2 supporting datasets | 1700025G04Rikem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
increased circulating bilirubin level | 1 supporting dataset | 1700025G04Rikem1(IMPC)Mbp | homozygote | Early adult | 1.3x10-6 | ||
anophthalmia | 1 supporting dataset | 1700025G04Rikem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
abnormal eye morphology | 1 supporting dataset | 1700025G04Rikem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
abnormal lymph node morphology | 2 supporting datasets | 1700025G04Rikem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
abnormal vocalization | 1 supporting dataset | 1700025G04Rikem1(IMPC)Mbp | homozygote | Early adult | 9.38x10-6 | ||
abnormal spleen morphology | 2 supporting datasets | 1700025G04Rikem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
enlarged spleen | 2 supporting datasets | 1700025G04Rikem1(IMPC)Mbp | homozygote | Late adult | N/A * | ||
increased red blood cell distribution width | 1 supporting dataset | 1700025G04Rikem1(IMPC)Mbp | homozygote | Early adult | 3.98x10-6 | ||
increased mean corpuscular volume | 1 supporting dataset | 1700025G04Rikem1(IMPC)Mbp | homozygote | Early adult | 2.21x10-14 |
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Human diseases caused by 1700025G04Rik mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for 1700025G04Rik.
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1700025G04Rikem1(IMPC)Mbp | Exon Deletion | | mouse |
1700025G04Riktm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |