1700025G04Rik | RIKEN cDNA 1700025G04 gene

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological

11 No significant impact

7 Not tested

Gene metrics:10Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged lymph nodes2 supporting datasets1700025G04Rikem1(IMPC)MbphomozygoteLate adultN/A * 
increased circulating bilirubin level1 supporting dataset1700025G04Rikem1(IMPC)MbphomozygoteEarly adult1.3x10-6 
anophthalmia1 supporting dataset1700025G04Rikem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal eye morphology1 supporting dataset1700025G04Rikem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal lymph node morphology2 supporting datasets1700025G04Rikem1(IMPC)MbphomozygoteLate adultN/A * 
abnormal vocalization1 supporting dataset1700025G04Rikem1(IMPC)MbphomozygoteEarly adult9.38x10-6 
abnormal spleen morphology2 supporting datasets1700025G04Rikem1(IMPC)MbphomozygoteLate adultN/A * 
enlarged spleen2 supporting datasets1700025G04Rikem1(IMPC)MbphomozygoteLate adultN/A * 
increased red blood cell distribution width1 supporting dataset1700025G04Rikem1(IMPC)MbphomozygoteEarly adult3.98x10-6 
increased mean corpuscular volume1 supporting dataset1700025G04Rikem1(IMPC)MbphomozygoteEarly adult2.21x10-14 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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1700025G04Rikem1(IMPC)MbpExon Deletionmouse
1700025G04Riktm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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