Pacrg | PARK2 co-regulated
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Reproductive system Pigmentation Integument Behavior/neurological
12 No significant impact
7 Not tested
Data collections
Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased circulating HDL cholesterol level | 1 supporting dataset | Pacrgem1(IMPC)J | homozygote | Late adult | 7.67x10-5 | ||
| abnormal locomotor behavior | 1 supporting dataset | Pacrgem1(IMPC)J | homozygote | Late adult | 8.85x10-6 | ||
| male infertility | 1 supporting dataset | Pacrgem1(IMPC)J | homozygote | Early adult | N/A * | ||
| abnormal coat/hair pigmentation | 1 supporting dataset | Pacrgem1(IMPC)J | homozygote | Late adult | 8.57x10-6 |
| | | | | | | | | | |
Human diseases caused by Pacrg mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Pacrg.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Pacrgem1(IMPC)J | Exon Deletion | | mouse |