Sec62 | SEC62 homolog, preprotein translocation

GeneMGI:1916526Synonyms: HTP1, 3100002M17Rik, +3 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Pigmentation Integument Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal coat/hair pigmentation	1 supporting dataset	Sec62^em1(IMPC)J	heterozygote	Early adult	1.84x10^-6
embryonic lethality prior to organogenesis	1 supporting dataset	Sec62^em1(IMPC)J	homozygote	E9.5	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Sec62^em1(IMPC)J	homozygote	Early adult	N/A ^*
abnormal vocalization	1 supporting dataset	Sec62^em1(IMPC)J	heterozygote	Early adult	1.61x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Sec62.

Associated images

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Histopathology

There is no histopathology data found for Sec62.

IMPC related publications

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External links

No external links available for Sec62.

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*Sec62^em1(IMPC)J*	Exon Deletion	‌	mouse
*Sec62^{tm380515(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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