Ing2 | inhibitor of growth family, member 2

GeneMGI:1916510Synonyms: ING2, P33ING2, +2 more

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Hematopoietic system Behavior/neurological Mortality/aging

13 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

50Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased vertical activity	1 supporting dataset	Ing2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.52x10^-6
increased circulating bilirubin level	1 supporting dataset	Ing2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	9.21x10^-23
hyperactivity	6 supporting datasets	Ing2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.29x10^-12
increased mean corpuscular volume	1 supporting dataset	Ing2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	5.4x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Ing2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased circulating alanine transaminase level	1 supporting dataset	Ing2^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.94x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ing2.

Associated images

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Histopathology

There is no histopathology data found for Ing2.

IMPC related publications

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External links

No external links available for Ing2.

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*Ing2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Ing2^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Ing2^{tm88489(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes