Gtpbp4 | GTP binding protein 4

GeneMGI:1916487Synonyms: Nog1, 2610028C09Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Pigmentation Integument Hematopoietic system Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:5Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased mean corpuscular hemoglobin	1 supporting dataset	Gtpbp4^em1(IMPC)Tcp	heterozygote	Early adult	6.06x10^-9
preweaning lethality, complete penetrance	3 supporting datasets	Gtpbp4^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal coat/hair pigmentation	1 supporting dataset	Gtpbp4^em1(IMPC)Tcp	heterozygote	Early adult	3.86x10^-5
embryonic lethality prior to organogenesis	1 supporting dataset	Gtpbp4^em1(IMPC)Tcp	homozygote	E9.5	N/A ^*
decreased mean corpuscular volume	1 supporting dataset	Gtpbp4^em1(IMPC)Tcp	heterozygote	Early adult	7.83x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gtpbp4.

Associated images

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Histopathology

There is no histopathology data found for Gtpbp4.

IMPC related publications

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External links

No external links available for Gtpbp4.

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*Gtpbp4^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Gtpbp4^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Gtpbp4^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Gtpbp4^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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