Dhx16 | DEAH-box helicase 16

GeneMGI:1916442Synonyms: DEAH (Asp-Glu-Ala-His) box polypeptide 16, DBP2, +2 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological Mortality/aging Cardiovascular system

16 No significant impact

4 Not tested

Gene metrics:5Significant phenotypes
1Associated diseases
Expression examined in:50Adult tissues
62Embryo tissues

Phenotypes

thick ventricular wall1 supporting datasetDhx16tm1b(EUCOMM)WtsiheterozygoteEarly adult5.64x10-7 
embryonic lethality prior to organogenesis1 supporting datasetDhx16tm1b(EUCOMM)WtsihomozygoteE9.5N/A * 
preweaning lethality, complete penetrance3 supporting datasetsDhx16tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
abnormal retina blood vessel morphology1 supporting datasetDhx16tm1b(EUCOMM)WtsiheterozygoteEarly adult3.47x10-5 
decreased exploration in new environment1 supporting datasetDhx16tm1b(EUCOMM)WtsiheterozygoteEarly adult1.67x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Dhx16tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Dhx16tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Dhx16tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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