Gsdmd | gasdermin D

GeneMGI:1916396Synonyms: 1810036L03Rik, DF5L, +3 more

Physiological systems

14 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Cardiovascular system

13 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased heart left ventricle size1 supporting datasetGsdmdem1(IMPC)MarchomozygoteEarly adult9.94x10-6 
dilated heart left ventricle1 supporting datasetGsdmdem1(IMPC)MarchomozygoteEarly adult9.9x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gsdmdem1(IMPC)MarcDeletionmouse
Gsdmdtm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Gsdmdtm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Gsdmdtm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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