Cgrrf1 | cell growth regulator with ring finger domain 1

GeneMGI:1916368Synonyms: 1110038G02Rik, CGR19, +1 more

Physiological systems

18 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Hematopoietic system Skeleton Craniofacial

13 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:6Significant phenotypes

0Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased bone mineral content	1 supporting dataset	Cgrrf1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.44x10^-7
abnormal cranium morphology	1 supporting dataset	Cgrrf1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.88x10^-6
decreased bone mineral density	1 supporting dataset	Cgrrf1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	9.01x10^-7
decreased circulating serum albumin level	1 supporting dataset	Cgrrf1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	9.4x10^-5
increased CD5-positive gamma-delta T cell number	1 supporting dataset	Cgrrf1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
increased gamma-delta T cell number	1 supporting dataset	Cgrrf1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cgrrf1.

Associated images

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Histopathology

There is no histopathology data found for Cgrrf1.

IMPC related publications

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External links

No external links available for Cgrrf1.

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*Cgrrf1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Cgrrf1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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