Oxa1l | oxidase assembly 1-like
Physiological systems
19 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Behavior/neurological Mortality/aging Cardiovascular system
16 No significant impact
5 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
embryonic lethality prior to organogenesis | 1 supporting dataset | Oxa1lem1(IMPC)Bay | homozygote | E9.5 | N/A * | ||
increased heart left ventricle size | 1 supporting dataset | Oxa1lem1(IMPC)Bay | heterozygote | Early adult | 1.06x10-7 | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Oxa1lem1(IMPC)Bay | homozygote | Early adult | N/A * | ||
embryonic lethality prior to tooth bud stage | 1 supporting dataset | Oxa1lem1(IMPC)Bay | homozygote | E12.5 | N/A * | ||
thick ventricular wall | 1 supporting dataset | Oxa1lem1(IMPC)Bay | heterozygote | Early adult | 2.89x10-6 | ||
hypoalgesia | 1 supporting dataset | Oxa1lem1(IMPC)Bay | heterozygote | Early adult | 4.54x10-5 ** |
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External links
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Oxa1lem1(IMPC)Bay | Exon Deletion | | mouse |
Oxa1ltm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
Oxa1ltm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |