Oxa1l | oxidase assembly 1-like

GeneMGI:1916339Synonyms: 1810020M02Rik

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging Cardiovascular system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

embryonic lethality prior to organogenesis1 supporting datasetOxa1lem1(IMPC)BayhomozygoteE9.5N/A * 
increased heart left ventricle size1 supporting datasetOxa1lem1(IMPC)BayheterozygoteEarly adult1.06x10-7 
preweaning lethality, complete penetrance3 supporting datasetsOxa1lem1(IMPC)BayhomozygoteEarly adultN/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetOxa1lem1(IMPC)BayhomozygoteE12.5N/A * 
thick ventricular wall1 supporting datasetOxa1lem1(IMPC)BayheterozygoteEarly adult2.89x10-6 
hypoalgesia1 supporting datasetOxa1lem1(IMPC)BayheterozygoteEarly adult4.54x10-5 **
* Does not have a P-value assigned because it was manually marked as significant.
** Significant with a threshold of 1x10-3, check the Pain Sensitivity page for more information.
Download data as:  










* This parameter was manually assessed for significance.
** Significant with a threshold of 1x10-3, check the Pain Sensitivity page for more information.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Oxa1lem1(IMPC)BayExon Deletionmouse
Oxa1ltm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Oxa1ltm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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