Mcts1 | malignant T cell amplified sequence 1

GeneMGI:1916245Synonyms: MCT-1, 1500019M23Rik

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Growth/size/body region Vision/eye Hematopoietic system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal eye morphology	1 supporting dataset	Mcts1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged spleen	1 supporting dataset	Mcts1^em1(IMPC)Mbp	hemizygote	Early adult	N/A ^*
cataract	1 supporting dataset	Mcts1^em1(IMPC)Mbp	homozygote	Early adult	7.32x10^-5
microphthalmia	1 supporting dataset	Mcts1^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Mcts1.

Associated images

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Histopathology

There is no histopathology data found for Mcts1.

IMPC related publications

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External links

No external links available for Mcts1.

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*Mcts1^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Mcts1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Mcts1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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