Med27 | mediator complex subunit 27

GeneMGI:1916225Synonyms: Crsp8, 1500015J03Rik, +2 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Vision/eye Mortality/aging Cardiovascular system

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	3 supporting datasets	Med27^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal retina blood vessel morphology	1 supporting dataset	Med27^em1(IMPC)Bay	heterozygote	Early adult	5.08x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Med27.

Associated images

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Histopathology

There is no histopathology data found for Med27.

IMPC related publications

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External links

No external links available for Med27.

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*Med27^em1(IMPC)Bay*	Exon Deletion	‌	mouse
*Med27^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell
*Med27^{tm231513(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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