Cdan1 | codanin 1

GeneMGI:1916218Synonyms: CDA1, CDA-I, +2 more

Physiological systems

22 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Embryo Growth/size/body region Hematopoietic system Mortality/aging

15 No significant impact

2 Not tested

Gene metrics:10Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
30Embryo tissues

Phenotypes

thrombocytopenia1 supporting datasetCdan1tm1b(KOMP)WtsiheterozygoteEarly adult6.09x10-5 
abnormal embryo size1 supporting datasetCdan1tm1b(KOMP)WtsiheterozygoteE9.5N/A * 
preweaning lethality, incomplete penetrance2 supporting datasetsCdan1tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
abnormal testis morphology1 supporting datasetCdan1tm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
increased circulating alanine transaminase level1 supporting datasetCdan1tm1b(KOMP)WtsiheterozygoteEarly adult3.59x10-9 
embryonic growth retardation1 supporting datasetCdan1tm1b(KOMP)WtsiheterozygoteE9.5N/A * 
small testis1 supporting datasetCdan1tm1b(KOMP)WtsiheterozygoteEarly adultN/A * 
preweaning lethality, complete penetrance1 supporting datasetCdan1tm1b(KOMP)WtsihomozygoteEarly adultN/A * 
prenatal lethality prior to heart atrial septation1 supporting datasetCdan1tm1b(KOMP)WtsihomozygoteE15.5N/A * 
embryonic lethality prior to organogenesis1 supporting datasetCdan1tm1b(KOMP)WtsihomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cdan1em1(IMPC)WtsiPoint Mutationmouse
Cdan1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Cdan1tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Cdan1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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