Ngdn | neuroguidin, EIF4E binding protein

GeneMGI:1916216Synonyms: Ngd, neuroguidin, +1 more

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Vision/eye Mortality/aging

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating HDL cholesterol level1 supporting datasetNgdntm1b(EUCOMM)WtsiheterozygoteEarly adult1.07x10-5 
hydrometra1 supporting datasetNgdntm1b(EUCOMM)WtsiheterozygoteEarly adultN/A * 
abnormal lens morphology1 supporting datasetNgdntm1b(EUCOMM)WtsiheterozygoteEarly adult2.57x10-5 
decreased circulating cholesterol level1 supporting datasetNgdntm1b(EUCOMM)WtsiheterozygoteEarly adult6.72x10-5 
preweaning lethality, complete penetrance1 supporting datasetNgdntm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ngdntm1(NCOM)MfgcReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Ngdntm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Ngdntm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Ngdntm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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