Tlcd3b | TLC domain containing 3B
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Growth/size/body region Nervous system Vision/eye Behavior/neurological
14 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased total retina thickness | 2 supporting datasets | Tlcd3bem1(IMPC)Bay | homozygote | Early adult | 1.38x10-8 | ||
| decreased prepulse inhibition | 4 supporting datasets | Tlcd3bem1(IMPC)Bay | homozygote | Early adult | 2.99x10-7 | ||
| abnormal retina outer nuclear layer morphology | 2 supporting datasets | Tlcd3bem1(IMPC)Bay | homozygote | Early adult | 3.82x10-33 | ||
| decreased startle reflex | 1 supporting dataset | Tlcd3bem1(IMPC)Bay | homozygote | Early adult | 6.79x10-5 | ||
| abnormal retina morphology | 1 supporting dataset | Tlcd3bem1(IMPC)Bay | homozygote | Early adult | 4.25x10-5 | ||
| decreased body length | 1 supporting dataset | Tlcd3bem1(IMPC)Bay | homozygote | Early adult | 1.09x10-5 |
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External links
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| Tlcd3bem1(IMPC)Bay | Exon Deletion | | mouse |
| Tlcd3btm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Tlcd3btm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | es cell |