Pink1 | PTEN induced putative kinase 1

GeneMGI:1916193Synonyms: 1190006F07Rik, brpk

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Hematopoietic system Skeleton

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



decreased bone mineral content	2 supporting datasets	Pink1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.21x10^-5
decreased bone mineral density	1 supporting dataset	Pink1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.36x10^-7
decreased mean platelet volume	1 supporting dataset	Pink1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.69x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Pink1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Pink1.

IMPC related publications

Loading...

External links

No external links available for Pink1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Pink1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Pink1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Pink1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

My Genes