Pink1 | PTEN induced putative kinase 1

GeneMGI:1916193Synonyms: 1190006F07Rik, brpk

Physiological systems

18 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Hematopoietic system Skeleton

16 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



decreased bone mineral content	2 supporting datasets	Pink1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	2.21x10^-5
decreased bone mineral density	1 supporting dataset	Pink1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.36x10^-7
decreased mean platelet volume	1 supporting dataset	Pink1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	3.69x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pink1.

Associated images

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Histopathology

There is no histopathology data found for Pink1.

IMPC related publications

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External links

No external links available for Pink1.

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*Pink1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Pink1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pink1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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