Trmt1l | tRNA methyltransferase 1 like

GeneMGI:1916185Synonyms: Trm1-like, 1190005F20Rik

Physiological systems

10 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system

8 No significant impact

14 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased circulating alanine transaminase level1 supporting datasetTrmt1lGt(W027A02)WrsthomozygoteEarly adult9.05x10-5 
abnormal iron homeostasis1 supporting datasetTrmt1lGt(W027A02)WrsthomozygoteEarly adult3.94x10-6 
thrombocytopenia1 supporting datasetTrmt1lGt(W027A02)WrsthomozygoteEarly adult2.43x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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