Tmcc2 | transmembrane and coiled-coil domains 2

GeneMGI:1916125Synonyms: 1110063G11Rik

Physiological systems

22 / 24 physiological systems tested

12 Significantly impacted by the knock-out

Immune system Endocrine/exocrine gland Integument Embryo Growth/size/body region Digestive/alimentary Vision/eye Liver/biliary system Hematopoietic system Behavior/neurological Mortality/aging Cardiovascular system

10 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:15Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal cecum morphology	2 supporting datasets	Tmcc2^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
no spontaneous movement	1 supporting dataset	Tmcc2^em1(IMPC)Mbp	heterozygote	E18.5	N/A ^*
enlarged gallbladder	1 supporting dataset	Tmcc2^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
decreased mean corpuscular volume	1 supporting dataset	Tmcc2^em1(IMPC)Mbp	heterozygote	Early adult	2.47x10^-5
abnormal skin appearance	1 supporting dataset	Tmcc2^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
no spontaneous movement	1 supporting dataset	Tmcc2^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
abnormal placenta vasculature	1 supporting dataset	Tmcc2^em1(IMPC)Mbp	homozygote	E18.5	N/A ^*
enlarged spleen	1 supporting dataset	Tmcc2^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
enlarged cecum	2 supporting datasets	Tmcc2^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal retina blood vessel morphology	1 supporting dataset	Tmcc2^em1(IMPC)Mbp	heterozygote	Early adult	2.32x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tmcc2.

Associated images

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Histopathology

There is no histopathology data found for Tmcc2.

IMPC related publications

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External links

No external links available for Tmcc2.

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*Tmcc2^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Tmcc2^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tmcc2^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Tmcc2^{tm45181(L1L2_gt0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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