Mrps18c | mitochondrial ribosomal protein S18C

GeneMGI:1915985Synonyms: 1110037D14Rik

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Mortality/aging

15 No significant impact

6 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
25Embryo tissues

Phenotypes

prenatal lethality1 supporting datasetMrps18ctm1.1(KOMP)VlcghomozygoteE18.5N/A * 
embryonic lethality prior to organogenesis1 supporting datasetMrps18ctm1.1(KOMP)VlcghomozygoteE9.5N/A * 
decreased circulating creatinine level1 supporting datasetMrps18ctm1.1(KOMP)VlcgheterozygoteEarly adult6.3x10-6 
preweaning lethality, complete penetrance1 supporting datasetMrps18ctm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
decreased hematocrit1 supporting datasetMrps18ctm1.1(KOMP)VlcgheterozygoteEarly adult4.93x10-7 
decreased erythrocyte cell number1 supporting datasetMrps18ctm1.1(KOMP)VlcgheterozygoteEarly adult1.13x10-5 
decreased hemoglobin content1 supporting datasetMrps18ctm1.1(KOMP)VlcgheterozygoteEarly adult4.32x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mrps18ctm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Mrps18ctm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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