Smyd2 | SET and MYND domain containing 2

GeneMGI:1915889Synonyms: KMT3C, Zmynd14, +1 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

17 No significant impact

5 Not tested

Data collections

Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:45Adult tissues
0Embryo tissues

Phenotypes

abnormal behavior1 supporting datasetSmyd2tm1a(KOMP)WtsihomozygoteEarly adult4.29x10-5 
increased circulating LDL cholesterol level1 supporting datasetSmyd2tm1a(KOMP)WtsihomozygoteEarly adult1.62x10-8 
increased circulating HDL cholesterol level1 supporting datasetSmyd2tm1a(KOMP)WtsihomozygoteEarly adult9.68x10-6 
increased circulating cholesterol level1 supporting datasetSmyd2tm1a(KOMP)WtsihomozygoteEarly adult5.62x10-5 
decreased circulating alanine transaminase level1 supporting datasetSmyd2tm1a(KOMP)WtsihomozygoteEarly adult2.12x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Smyd2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Smyd2tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Smyd2tm3a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell

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