Ube2c | ubiquitin-conjugating enzyme E2C

GeneMGI:1915862Synonyms: 1110015A16Rik, D2Ertd695e

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Embryo Growth/size/body region Behavior/neurological Mortality/aging

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

46Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



preweaning lethality, complete penetrance	1 supporting dataset	Ube2c^{tm1.1(KOMP)Wtsi}	homozygote	Early adult	N/A ^*
embryonic growth retardation	1 supporting dataset	Ube2c^{tm1.1(KOMP)Wtsi}	homozygote	E12.5	N/A ^*
hyperactivity	2 supporting datasets	Ube2c^{tm1.1(KOMP)Wtsi}	heterozygote	Early adult	9.56x10^-5
embryonic growth retardation	1 supporting dataset	Ube2c^{tm1.1(KOMP)Wtsi}	heterozygote	E12.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ube2c.

Associated images

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Histopathology

There is no histopathology data found for Ube2c.

IMPC related publications

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External links

No external links available for Ube2c.

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*Ube2c^{tm1(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell mouse
*Ube2c^{tm1.1(KOMP)Wtsi}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Ube2c^{tm462023(Ifitm2_intron_L1L2_GT2_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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