Polrmt | polymerase (RNA) mitochondrial (DNA directed)
Physiological systems
22 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Immune system Nervous system Behavior/neurological Mortality/aging
18 No significant impact
2 Not tested
Data collections
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| no spontaneous movement | 1 supporting dataset | Polrmtem1(IMPC)Mbp | heterozygote | E18.5 | N/A * | ||
| preweaning lethality, incomplete penetrance | 3 supporting datasets | Polrmtem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Polrmtem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| enlarged lymph nodes | 1 supporting dataset | Polrmtem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| hydrocephaly | 1 supporting dataset | Polrmtem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal lymph node morphology | 1 supporting dataset | Polrmtem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal brain morphology | 1 supporting dataset | Polrmtem1(IMPC)Mbp | heterozygote | Early adult | N/A * |
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External links
No external links available for Polrmt.
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| Polrmtem1(IMPC)Mbp | Exon Deletion | | mouse |
| Polrmttm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Polrmttm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Polrmttm2e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |