Mrpl58 | mitochondrial ribosomal protein L58
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Embryo Growth/size/body region Hematopoietic system Skeleton Mortality/aging
15 No significant impact
4 Not tested
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
| decreased bone mineral density | 1 supporting dataset | Mrpl58tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 8.8x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Mrpl58tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased hematocrit | 1 supporting dataset | Mrpl58tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.71x10-13 | ||
| abnormal embryo size | 1 supporting dataset | Mrpl58tm1b(EUCOMM)Hmgu | homozygote | E15.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Mrpl58tm1b(EUCOMM)Hmgu | homozygote | E18.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Mrpl58tm1b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Mrpl58tm1b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * | ||
| embryonic growth retardation | 1 supporting dataset | Mrpl58tm1b(EUCOMM)Hmgu | homozygote | E15.5 | N/A * |
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External links
No external links available for Mrpl58.
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| Mrpl58tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Mrpl58tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Mrpl58tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Mrpl58tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |