Cgref1 | cell growth regulator with EF hand domain 1

GeneMGI:1915817Synonyms: CGR11, 1110004G24Rik

Physiological systems

17 / 24 physiological systems tested

8 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Pigmentation Integument Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system

9 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal coat/hair pigmentation1 supporting datasetCgref1em1(IMPC)JhomozygoteLate adult5.79x10-6 
abnormal vocalization1 supporting datasetCgref1em1(IMPC)JhomozygoteLate adult1.64x10-11 
decreased circulating alkaline phosphatase level1 supporting datasetCgref1em1(IMPC)JhomozygoteEarly adult6.15x10-5 
increased heart weight1 supporting datasetCgref1em1(IMPC)JhomozygoteLate adult9.18x10-6 
abnormal coat/ hair morphology1 supporting datasetCgref1em1(IMPC)JhomozygoteLate adult2.58x10-5 
increased leukocyte cell number1 supporting datasetCgref1em1(IMPC)JhomozygoteLate adult9.21x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cgref1em1(IMPC)JExon Deletionmouse

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