Nufip2 | nuclear FMR1 interacting protein 2

GeneMGI:1915814Synonyms: 1110001M19Rik, 9530056D24Rik

Physiological systems

19 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Homeostasis/metabolism Embryo Growth/size/body region Nervous system Hematopoietic system Behavior/neurological Mortality/aging

12 No significant impact

5 Not tested

Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating alkaline phosphatase level1 supporting datasetNufip2em1(IMPC)JheterozygoteEarly adult6.16x10-5 
increased startle reflex1 supporting datasetNufip2em1(IMPC)JheterozygoteEarly adult6.19x10-6 
decreased mean corpuscular hemoglobin1 supporting datasetNufip2em1(IMPC)JheterozygoteEarly adult1.69x10-6 
abnormal neural tube closure1 supporting datasetNufip2em1(IMPC)JhomozygoteE9.5N/A * 
preweaning lethality, complete penetrance1 supporting datasetNufip2em1(IMPC)JhomozygoteEarly adultN/A * 
decreased prepulse inhibition1 supporting datasetNufip2em1(IMPC)JheterozygoteEarly adult7.53x10-5 
abnormal embryo size1 supporting datasetNufip2em1(IMPC)JhomozygoteE18.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Nufip2em1(IMPC)JExon Deletionmouse
Nufip2tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Nufip2tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Nufip2tm2e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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