Ecscr | endothelial cell surface expressed chemotaxis and apoptosis regulator

GeneMGI:1915795Synonyms: ARIA, 1110006O17Rik

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Nervous system Hematopoietic system Renal/urinary system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal epididymis morphology	1 supporting dataset	Ecscr^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal seminal vesicle morphology	1 supporting dataset	Ecscr^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
enlarged epididymis	1 supporting dataset	Ecscr^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal kidney morphology	1 supporting dataset	Ecscr^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Ecscr^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
small thymus	1 supporting dataset	Ecscr^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
small seminal vesicle	1 supporting dataset	Ecscr^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal spinal cord morphology	1 supporting dataset	Ecscr^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	1 supporting dataset	Ecscr^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Ecscr.

Associated images

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Histopathology

There is no histopathology data found for Ecscr.

IMPC related publications

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External links

No external links available for Ecscr.

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*Ecscr^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Ecscr^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Ecscr^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ecscr^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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