Lmbrd1 | LMBR1 domain containing 1
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Embryo Growth/size/body region Hematopoietic system Mortality/aging
15 No significant impact
5 Not tested
Data collections
Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Lmbrd1tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Lmbrd1tm1b(EUCOMM)Hmgu | homozygote | E12.5 | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Lmbrd1tm1b(EUCOMM)Hmgu | heterozygote | E9.5 | N/A * | ||
| decreased mean corpuscular hemoglobin | 1 supporting dataset | Lmbrd1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 8.5x10-5 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Lmbrd1tm1b(EUCOMM)Hmgu | homozygote | E9.5 | N/A * |
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Human diseases caused by Lmbrd1 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Lmbrd1.
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| Lmbrd1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Lmbrd1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Lmbrd1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |