Lmbrd1 | LMBR1 domain containing 1

GeneMGI:1915671Synonyms: 0910001K20Rik

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Embryo Growth/size/body region Hematopoietic system Mortality/aging

15 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
29Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsLmbrd1tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
embryonic lethality prior to tooth bud stage1 supporting datasetLmbrd1tm1b(EUCOMM)HmguhomozygoteE12.5N/A * 
abnormal embryo size1 supporting datasetLmbrd1tm1b(EUCOMM)HmguheterozygoteE9.5N/A * 
decreased mean corpuscular hemoglobin1 supporting datasetLmbrd1tm1b(EUCOMM)HmguheterozygoteEarly adult8.5x10-5 
embryonic lethality prior to organogenesis1 supporting datasetLmbrd1tm1b(EUCOMM)HmguhomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lmbrd1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Lmbrd1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Lmbrd1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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