Ndufs3 | NADH:ubiquinone oxidoreductase core subunit S3

GeneMGI:1915599Synonyms: 0610010M09Rik

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system Mortality/aging

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased circulating serum albumin level	1 supporting dataset	Ndufs3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.92x10^-6
decreased erythrocyte cell number	1 supporting dataset	Ndufs3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	6.16x10^-5
increased heart weight	1 supporting dataset	Ndufs3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	9.54x10^-16
preweaning lethality, complete penetrance	1 supporting dataset	Ndufs3^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
decreased total body fat amount	1 supporting dataset	Ndufs3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	1.77x10^-7
decreased circulating HDL cholesterol level	1 supporting dataset	Ndufs3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.51x10^-6
decreased circulating cholesterol level	1 supporting dataset	Ndufs3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	4.93x10^-6
increased startle reflex	2 supporting datasets	Ndufs3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	2.06x10^-5
increased circulating phosphate level	1 supporting dataset	Ndufs3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	5.04x10^-6
increased circulating sodium level	1 supporting dataset	Ndufs3^{tm1a(EUCOMM)Wtsi}	heterozygote	Early adult	3.31x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Ndufs3.

Associated images

Loading...

Histopathology

There is no histopathology data found for Ndufs3.

IMPC related publications

Loading...

External links

No external links available for Ndufs3.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Ndufs3^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Ndufs3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Ndufs3^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

My Genes