Lypd2 | Ly6/Plaur domain containing 2

GeneMGI:1915561Synonyms: 0610005K03Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Immune system Hematopoietic system

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased neutrophil cell number2 supporting datasetsLypd2em1(IMPC)MarchomozygoteEarly adult2.05x10-7 
increased lymphocyte cell number1 supporting datasetLypd2em1(IMPC)MarchomozygoteEarly adult6.49x10-8 
thrombocytopenia1 supporting datasetLypd2em1(IMPC)MarchomozygoteEarly adult4.2x10-6 
decreased monocyte cell number1 supporting datasetLypd2em1(IMPC)MarchomozygoteEarly adult1.31x10-6 
decreased mean platelet volume1 supporting datasetLypd2em1(IMPC)MarchomozygoteEarly adult1.41x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Lypd2em1(IMPC)MarcIndelmouse
Lypd2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Lypd2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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