Stt3b | STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)

GeneMGI:1915542Synonyms: Simp, 1300006C19Rik

Physiological systems

18 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Embryo Growth/size/body region Hematopoietic system Behavior/neurological Mortality/aging

12 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:9Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



decreased locomotor activity	1 supporting dataset	Stt3b^em1(IMPC)J	heterozygote	Early adult	2.17x10^-7
embryonic lethality prior to tooth bud stage	1 supporting dataset	Stt3b^em1(IMPC)J	homozygote	E12.5	N/A ^*
embryonic growth retardation	1 supporting dataset	Stt3b^em1(IMPC)J	homozygote	E9.5	N/A ^*
decreased exploration in new environment	1 supporting dataset	Stt3b^em1(IMPC)J	heterozygote	Early adult	6.12x10^-5
decreased mean corpuscular hemoglobin	1 supporting dataset	Stt3b^em1(IMPC)J	heterozygote	Early adult	4.82x10^-9
increased circulating cholesterol level	1 supporting dataset	Stt3b^em1(IMPC)J	heterozygote	Early adult	5.06x10^-5
increased circulating alanine transaminase level	1 supporting dataset	Stt3b^em1(IMPC)J	heterozygote	Early adult	3.56x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Stt3b^em1(IMPC)J	homozygote	Early adult	N/A ^*
increased circulating bilirubin level	1 supporting dataset	Stt3b^em1(IMPC)J	heterozygote	Early adult	4.33x10^-12

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Stt3b.

Associated images

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Histopathology

There is no histopathology data found for Stt3b.

IMPC related publications

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External links

No external links available for Stt3b.

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*Stt3b^em1(IMPC)J*	Exon Deletion	‌	mouse
*Stt3b^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Stt3b^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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