Toe1 | target of EGR1, member 1 (nuclear)

GeneMGI:1915526Synonyms: 4930584N22Rik, 4933424D16Rik

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological Mortality/aging Renal/urinary system

15 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

limb grasping1 supporting datasetToe1tm1.1(KOMP)VlcgheterozygoteEarly adult2.2x10-5 
preweaning lethality, complete penetrance1 supporting datasetToe1tm1.1(KOMP)VlcghomozygoteEarly adultN/A * 
decreased urine magnesium level1 supporting datasetToe1tm1.1(KOMP)VlcgheterozygoteEarly adult6.97x10-7 
embryonic lethality prior to organogenesis1 supporting datasetToe1tm1.1(KOMP)VlcghomozygoteE9.5N/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Toe1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
mouse
Toe1tm1(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Toe1tm1.1(KOMP)VlcgReporter-tagged deletion allele (post Cre, with no selection cassette)mouse

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