Toe1 | target of EGR1, member 1 (nuclear)
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Behavior/neurological Mortality/aging Renal/urinary system
15 No significant impact
5 Not tested
Data collections
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues
limb grasping | 1 supporting dataset | Toe1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 2.2x10-5 | ||
preweaning lethality, complete penetrance | 1 supporting dataset | Toe1tm1.1(KOMP)Vlcg | homozygote | Early adult | N/A * | ||
decreased urine magnesium level | 1 supporting dataset | Toe1tm1.1(KOMP)Vlcg | heterozygote | Early adult | 6.97x10-7 | ||
embryonic lethality prior to organogenesis | 1 supporting dataset | Toe1tm1.1(KOMP)Vlcg | homozygote | E9.5 | N/A * |
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External links
No external links available for Toe1.
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Toe1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
Toe1tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
Toe1tm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |