Agpat4 | 1-acylglycerol-3-phosphate O-acyltransferase 4

GeneMGI:1915512Synonyms: 1500003P24Rik

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Adipose tissue Growth/size/body region Skeleton

15 No significant impact

5 Not tested

Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

abnormal bone structure1 supporting datasetAgpat4tm1b(KOMP)WtsihomozygoteEarly adult8.54x10-6 
decreased bone mineral content2 supporting datasetsAgpat4tm1b(KOMP)WtsihomozygoteEarly adult1.28x10-7 
increased total body fat amount2 supporting datasetsAgpat4tm1b(KOMP)WtsihomozygoteEarly adult2.07x10-10 
decreased lean body mass2 supporting datasetsAgpat4tm1b(KOMP)WtsihomozygoteEarly adult3.51x10-7 
increased fasting circulating glucose level1 supporting datasetAgpat4tm1b(KOMP)WtsihomozygoteEarly adult1.97x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Agpat4tm174604(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Agpat4tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Agpat4tm1b(KOMP)WtsiReporter-tagged deletion allele (with selection cassette)mouse

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