Ift80 | intraflagellar transport 80
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Limbs/digits/tail Hematopoietic system Skeleton Mortality/aging
12 No significant impact
7 Not tested
Data collections
Gene metrics:6Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal pelvic girdle bone morphology | 1 supporting dataset | Ift80tm1a(KOMP)Wtsi | homozygote | Early adult | 2.38x10-5 | ||
| abnormal radius morphology | 1 supporting dataset | Ift80tm1a(KOMP)Wtsi | heterozygote | Early adult | 2.87x10-5 | ||
| increased blood urea nitrogen level | 1 supporting dataset | Ift80tm1a(KOMP)Wtsi | homozygote | Early adult | 3.25x10-5 | ||
| increased red blood cell distribution width | 1 supporting dataset | Ift80tm1a(KOMP)Wtsi | heterozygote | Early adult | 4.6x10-8 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Ift80tm1a(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal ulna morphology | 1 supporting dataset | Ift80tm1a(KOMP)Wtsi | heterozygote | Early adult | 1.67x10-5 |
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Human diseases caused by Ift80 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
This gene doesn't have any significant Histopathology hits. Click here to see the raw data
External links
No external links available for Ift80.
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| Ift80tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Ift80tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |
| Ift80tm2a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Ift80tm2e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |