Ift80 | intraflagellar transport 80

GeneMGI:1915509Synonyms: Wdr56, 4921524P20Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Limbs/digits/tail Hematopoietic system Skeleton Mortality/aging

12 No significant impact

7 Not tested

Gene metrics:6Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal pelvic girdle bone morphology1 supporting datasetIft80tm1a(KOMP)WtsihomozygoteEarly adult2.38x10-5 
abnormal radius morphology1 supporting datasetIft80tm1a(KOMP)WtsiheterozygoteEarly adult2.87x10-5 
increased blood urea nitrogen level1 supporting datasetIft80tm1a(KOMP)WtsihomozygoteEarly adult3.25x10-5 
increased red blood cell distribution width1 supporting datasetIft80tm1a(KOMP)WtsiheterozygoteEarly adult4.6x10-8 
preweaning lethality, incomplete penetrance1 supporting datasetIft80tm1a(KOMP)WtsihomozygoteEarly adultN/A * 
abnormal ulna morphology1 supporting datasetIft80tm1a(KOMP)WtsiheterozygoteEarly adult1.67x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Ift80tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Ift80tm1e(KOMP)WtsiTargeted, non-conditional allelees cell
Ift80tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
Ift80tm2e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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