Tubb4b | tubulin, beta 4B class IVB

GeneMGI:1915472Synonyms: Tubb2c, 4930542G03Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Integument Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal coat appearance	3 supporting datasets	Tubb4b^em1(IMPC)J	heterozygote	Early adult	9.46x10^-13
abnormal coat/ hair morphology	1 supporting dataset	Tubb4b^em1(IMPC)J	heterozygote	Early adult	2.71x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Tubb4b^em1(IMPC)J	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Tubb4b.

Associated images

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Histopathology

There is no histopathology data found for Tubb4b.

IMPC related publications

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External links

No external links available for Tubb4b.

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*Tubb4b^em1(IMPC)J*	Exon Deletion	‌	mouse
*Tubb4b^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Tubb4b^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Tubb4b^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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