Diras2 | DIRAS family, GTP-binding RAS-like 2

GeneMGI:1915453Synonyms: 2900052J15Rik

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Skeleton Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased bone mineral density1 supporting datasetDiras2em1(IMPC)JhomozygoteEarly adult8.27x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetDiras2em1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Order Mouse and ES Cells

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Diras2em1(IMPC)JIntra-exon deletionmouse
Diras2tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Diras2tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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