Fam135a | family with sequence similarity 135, member A

GeneMGI:1915437Synonyms: 4921533L14Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Integument Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:13Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased locomotor activity	2 supporting datasets	Fam135a^em1(IMPC)Tcp	homozygote	Early adult	9.02x10^-6
abnormal retina blood vessel morphology	1 supporting dataset	Fam135a^em1(IMPC)Tcp	homozygote	Early adult	6.24x10^-5
increased mean corpuscular hemoglobin concentration	1 supporting dataset	Fam135a^em1(IMPC)Tcp	homozygote	Early adult	7.59x10^-5
increased thigmotaxis	2 supporting datasets	Fam135a^em1(IMPC)Tcp	homozygote	Early adult	9.75x10^-5
increased anxiety-related response	1 supporting dataset	Fam135a^em1(IMPC)Tcp	homozygote	Early adult	3.7x10^-6
cataract	1 supporting dataset	Fam135a^em1(IMPC)Tcp	homozygote	Early adult	3.29x10^-7
decreased mean corpuscular hemoglobin	1 supporting dataset	Fam135a^em1(IMPC)Tcp	homozygote	Early adult	2.84x10^-7
abnormal behavior	1 supporting dataset	Fam135a^em1(IMPC)Tcp	homozygote	Early adult	9.75x10^-5
abnormal retina vasculature morphology	1 supporting dataset	Fam135a^em1(IMPC)Tcp	homozygote	Early adult	7.08x10^-5
decreased mean corpuscular volume	1 supporting dataset	Fam135a^em1(IMPC)Tcp	homozygote	Early adult	1.05x10^-13

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fam135a.

Associated images

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Histopathology

There is no histopathology data found for Fam135a.

IMPC related publications

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External links

No external links available for Fam135a.

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*Fam135a^em1(IMPC)Tcp*	Exon Deletion	‌	mouse
*Fam135a^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Fam135a^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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