Gcsh | glycine cleavage system protein H (aminomethyl carrier)
Physiological systems
17 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Immune system Hematopoietic system Mortality/aging
14 No significant impact
7 Not tested
Data collections
Gene metrics:5Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased basophil cell number | 2 supporting datasets | Gcshem1(IMPC)H | heterozygote | Early adult | 1.19x10-9 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Gcshem1(IMPC)H | homozygote | Early adult | N/A * | ||
| increased mean corpuscular hemoglobin | 1 supporting dataset | Gcshem1(IMPC)H | heterozygote | Early adult | 3.45x10-5 | ||
| increased mean corpuscular volume | 1 supporting dataset | Gcshem1(IMPC)H | heterozygote | Early adult | 3.26x10-6 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Gcshem1(IMPC)H | homozygote | E9.5 | N/A * |
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External links
No external links available for Gcsh.
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| Gcshem1(IMPC)H | Exon Deletion | | mouse |
| Gcshtm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell |
| Gcshtm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Gcshtm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Gcshtm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |