Cops8 | COP9 signalosome subunit 8
Physiological systems
22 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Cardiovascular system Mortality/aging
16 No significant impact
2 Not tested
Data collections
Gene metrics:8Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| enlarged heart | 1 supporting dataset | Cops8em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Cops8em1(IMPC)Ccpcz | homozygote | E12.5 | N/A * | ||
| abnormal spleen morphology | 1 supporting dataset | Cops8em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| abnormal heart morphology | 1 supporting dataset | Cops8em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| abnormal thymus morphology | 1 supporting dataset | Cops8em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| enlarged thymus | 1 supporting dataset | Cops8em1(IMPC)Ccpcz | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Cops8em1(IMPC)Ccpcz | homozygote | E9.5 | N/A * | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Cops8em1(IMPC)Ccpcz | homozygote | Early adult | N/A * |
| | | | | | | | | | |
External links
No external links available for Cops8.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Cops8em1(IMPC)Ccpcz | Exon Deletion | | mouse |
| Cops8tm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell |
| Cops8tm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | es cell |