Entr1 | endosome associated trafficking regulator 1

GeneMGI:1915362Synonyms: C330016H24Rik, C630038K21Rik, +1 more

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Integument Growth/size/body region Liver/biliary system Hematopoietic system Cardiovascular system Renal/urinary system

11 No significant impact

4 Not tested

Gene metrics:17Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal urinary bladder morphology1 supporting datasetEntr1em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal seminal vesicle morphology1 supporting datasetEntr1em1(IMPC)MbphomozygoteLate adultN/A * 
enlarged ovary1 supporting datasetEntr1em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal testis morphology1 supporting datasetEntr1em1(IMPC)MbphomozygoteLate adultN/A * 
enlarged urinary bladder1 supporting datasetEntr1em1(IMPC)MbphomozygoteLate adultN/A * 
increased circulating calcium level1 supporting datasetEntr1em1(IMPC)MbphomozygoteEarly adult6.17x10-5 
small testis1 supporting datasetEntr1em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal liver morphology1 supporting datasetEntr1em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal ovary morphology1 supporting datasetEntr1em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal heart morphology1 supporting datasetEntr1em1(IMPC)MbphomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Entr1em1(IMPC)MbpInter-exon deletionmouse
Entr1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Entr1tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Entr1tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Entr1tm2a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell

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