Cibar1 | CBY1 interacting BAR domain containing 1

GeneMGI:1915349Synonyms: Fam92a, 6720467C03Rik

Physiological systems

18 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Limbs/digits/tail Hematopoietic system Skeleton

11 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:45Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased circulating glycerol level	1 supporting dataset	Cibar1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	3.67x10^-5
decreased total body fat amount	1 supporting dataset	Cibar1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.93x10^-6
abnormal humerus morphology	1 supporting dataset	Cibar1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.54x10^-10
decreased hematocrit	1 supporting dataset	Cibar1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	6.91x10^-5
decreased leukocyte cell number	1 supporting dataset	Cibar1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	8.63x10^-9
improved glucose tolerance	1 supporting dataset	Cibar1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	2.56x10^-6
increased circulating amylase level	1 supporting dataset	Cibar1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.67x10^-5
decreased hemoglobin content	1 supporting dataset	Cibar1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	4.6x10^-5
increased lean body mass	1 supporting dataset	Cibar1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	1.53x10^-6
decreased erythrocyte cell number	1 supporting dataset	Cibar1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	5.33x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cibar1.

Associated images

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Histopathology

There is no histopathology data found for Cibar1.

IMPC related publications

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External links

No external links available for Cibar1.

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*Cibar1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Cibar1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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