Naa10 | N(alpha)-acetyltransferase 10, NatA catalytic subunit

GeneMGI:1915255Synonyms: 2310039H09Rik, Te2, +2 more

Physiological systems

21 / 24 physiological systems tested

16 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Integument Adipose tissue Growth/size/body region Hematopoietic system Cardiovascular system Renal/urinary system Homeostasis/metabolism Pigmentation Nervous system Vision/eye Liver/biliary system Respiratory system Behavior/neurological

5 No significant impact

3 Not tested

Gene metrics:33Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology1 supporting datasetNaa10em1(IMPC)MbphomozygoteLate adultN/A * 
enlarged spleen1 supporting datasetNaa10em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal skin morphology1 supporting datasetNaa10em1(IMPC)MbphemizygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetNaa10em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal kidney morphology1 supporting datasetNaa10em1(IMPC)MbphomozygoteLate adultN/A * 
abnormal skin morphology1 supporting datasetNaa10em1(IMPC)MbphemizygoteLate adultN/A * 
enlarged kidney1 supporting datasetNaa10em1(IMPC)MbphemizygoteLate adultN/A * 
decreased total body fat amount1 supporting datasetNaa10em1(IMPC)MbphomozygoteEarly adult5.13x10-5 
abnormal skin morphology1 supporting datasetNaa10em1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetNaa10em1(IMPC)MbphomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Naa10em1(IMPC)MbpExon Deletionmouse
Naa10tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Naa10tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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