Retreg3 | reticulophagy regulator family member 3

GeneMGI:1915248Synonyms: 1300010M03Rik, 4933404C01Rik, +1 more

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Growth/size/body region Nervous system Vision/eye Hematopoietic system

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:14Significant phenotypes

0Associated diseases

Expression examined in:50Adult tissues

42Embryo tissues

Phenotypes

Allele:

Phy. System:



increased blood urea nitrogen level	1 supporting dataset	Retreg3^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	1.82x10^-5
abnormal retina pigmentation	2 supporting datasets	Retreg3^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	5.34x10^-6
abnormal eye morphology	1 supporting dataset	Retreg3^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	9.43x10^-6
decreased prepulse inhibition	4 supporting datasets	Retreg3^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	1.11x10^-9
increased blood urea nitrogen level	1 supporting dataset	Retreg3^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	1.28x10^-5
abnormal retina morphology	1 supporting dataset	Retreg3^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	1.46x10^-6
increased lean body mass	1 supporting dataset	Retreg3^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	1.84x10^-5
abnormal retina morphology	2 supporting datasets	Retreg3^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	5.34x10^-6
increased circulating amylase level	1 supporting dataset	Retreg3^{tm2b(EUCOMM)Wtsi}	homozygote	Early adult	5.98x10^-11
decreased mean corpuscular hemoglobin concentration	1 supporting dataset	Retreg3^{tm2a(EUCOMM)Wtsi}	homozygote	Early adult	7.79x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Retreg3.

Associated images

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Histopathology

There is no histopathology data found for Retreg3.

IMPC related publications

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External links

No external links available for Retreg3.

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*Retreg3^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Retreg3^{tm2a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Retreg3^{tm2b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Retreg3^{tm2e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Retreg3^{tm3a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Retreg3^{tm95(pL1L2_GT2_DelLacZ_bsd)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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