Puf60 | poly-U binding splicing factor 60

GeneMGI:1915209Synonyms: 2410104I19Rik, 2810454F19Rik

Physiological systems

14 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Vision/eye Mortality/aging

12 No significant impact

10 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:2Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal retina outer nuclear layer morphology1 supporting datasetPuf60em1(IMPC)BayheterozygoteEarly adult1.02x10-5 
preweaning lethality, complete penetrance1 supporting datasetPuf60em1(IMPC)BayhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Puf60em1(IMPC)BayExon Deletionmouse
Puf60tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Puf60tm451311(L1L2_GT0_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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