U2surp | U2 snRNP-associated SURP domain containing
Physiological systems
18 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Behavior/neurological Skeleton Mortality/aging
13 No significant impact
6 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | U2surpem1(IMPC)J | homozygote | Early adult | N/A * | ||
| decreased locomotor activity | 4 supporting datasets | U2surpem1(IMPC)J | heterozygote | Early adult | 1.58x10-5 | ||
| decreased circulating glucose level | 1 supporting dataset | U2surpem1(IMPC)J | heterozygote | Early adult | 2.14x10-7 | ||
| increased hematocrit | 1 supporting dataset | U2surpem1(IMPC)J | heterozygote | Early adult | 3.16x10-6 | ||
| decreased bone mineral density | 1 supporting dataset | U2surpem1(IMPC)J | heterozygote | Early adult | 5.05x10-6 | ||
| increased erythrocyte cell number | 1 supporting dataset | U2surpem1(IMPC)J | heterozygote | Early adult | 9.97x10-5 |
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External links
No external links available for U2surp.
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| U2surpem1(IMPC)J | Exon Deletion | | mouse |
| U2surptm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| U2surptm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |