Nifk | nucleolar protein interacting with the FHA domain of MKI67
Physiological systems
21 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Vision/eye Cardiovascular system Mortality/aging
18 No significant impact
3 Not tested
Data collections
Gene metrics:9Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal vitreous body morphology | 1 supporting dataset | Nifkem1(IMPC)Mbp | heterozygote | Early adult | 1.63x10-5 | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Nifkem1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
| abnormal retina vasculature morphology | 1 supporting dataset | Nifkem1(IMPC)Mbp | heterozygote | Early adult | 1.96x10-6 | ||
| persistence of hyaloid vascular system | 1 supporting dataset | Nifkem1(IMPC)Mbp | heterozygote | Early adult | 6.96x10-8 | ||
| anophthalmia | 1 supporting dataset | Nifkem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| abnormal retina morphology | 1 supporting dataset | Nifkem1(IMPC)Mbp | heterozygote | Early adult | 9.81x10-6 | ||
| abnormal eye morphology | 1 supporting dataset | Nifkem1(IMPC)Mbp | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Nifkem1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
| cataract | 1 supporting dataset | Nifkem1(IMPC)Mbp | heterozygote | Early adult | 1.36x10-5 |
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External links
No external links available for Nifk.
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| Nifkem1(IMPC)Mbp | Exon Deletion | | mouse |
| Nifktm1a(EUCOMM)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Nifktm1e(EUCOMM)Wtsi | Targeted, non-conditional allele | | ES Cell |