Atp5mc2 | ATP synthase membrane subunit c locus 2
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Mortality/aging Cardiovascular system
15 No significant impact
5 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| abnormal retina morphology | 1 supporting dataset | Atp5mc2tm2b(EUCOMM)Hmgu | heterozygote | Early adult | 8.07x10-6 | ||
| abnormal lens morphology | 2 supporting datasets | Atp5mc2tm2b(EUCOMM)Hmgu | heterozygote | Early adult | 3.5x10-8 | ||
| decreased total retina thickness | 1 supporting dataset | Atp5mc2tm2b(EUCOMM)Hmgu | heterozygote | Early adult | 2.74x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Atp5mc2tm2b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| abnormal retina vasculature morphology | 1 supporting dataset | Atp5mc2tm2b(EUCOMM)Hmgu | heterozygote | Early adult | 8.32x10-6 | ||
| abnormal retina blood vessel morphology | 1 supporting dataset | Atp5mc2tm2b(EUCOMM)Hmgu | heterozygote | Early adult | 4.03x10-6 | ||
| increased fasting circulating glucose level | 1 supporting dataset | Atp5mc2tm2b(EUCOMM)Hmgu | heterozygote | Early adult | 9.19x10-5 |
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External links
No external links available for Atp5mc2.
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| Atp5mc2tm2a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Atp5mc2tm2b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |