Ufm1 | ubiquitin-fold modifier 1

GeneMGI:1915140Synonyms: 1810045K17Rik

Physiological systems

18 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Adipose tissue Growth/size/body region Muscle Hematopoietic system Skeleton Mortality/aging Cardiovascular system

10 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:10Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased lean body mass	2 supporting datasets	Ufm1^{em1(IMPC)Marc}	heterozygote	Early adult	2.75x10^-9
decreased bone mineral content	2 supporting datasets	Ufm1^{em1(IMPC)Marc}	heterozygote	Early adult	2.42x10^-9
decreased circulating total protein level	1 supporting dataset	Ufm1^{em1(IMPC)Marc}	heterozygote	Early adult	5.04x10^-5
decreased bone mineral density	1 supporting dataset	Ufm1^{em1(IMPC)Marc}	heterozygote	Early adult	2.56x10^-9
increased total body fat amount	2 supporting datasets	Ufm1^{em1(IMPC)Marc}	heterozygote	Early adult	1.75x10^-13
preweaning lethality, complete penetrance	1 supporting dataset	Ufm1^{em1(IMPC)Marc}	homozygote	Early adult	N/A ^*
decreased cardiac muscle contractility	1 supporting dataset	Ufm1^{em1(IMPC)Marc}	heterozygote	Early adult	2.83x10^-6
dilated heart left ventricle	1 supporting dataset	Ufm1^{em1(IMPC)Marc}	heterozygote	Early adult	2.56x10^-5
decreased red blood cell distribution width	1 supporting dataset	Ufm1^{em1(IMPC)Marc}	heterozygote	Early adult	2.21x10^-5
increased circulating triglyceride level	1 supporting dataset	Ufm1^{em1(IMPC)Marc}	heterozygote	Early adult	5.94x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Ufm1.

Associated images

Loading...

Histopathology

There is no histopathology data found for Ufm1.

IMPC related publications

Loading...

External links

No external links available for Ufm1.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Ufm1^{em1(IMPC)Marc}*	Deletion	‌	mouse
*Ufm1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Ufm1^{tm46149(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes