Brix1 | BRX1, biogenesis of ribosomes

GeneMGI:1915082Synonyms: Bxdc2, 1110064N10Rik

Physiological systems

16 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Immune system Hematopoietic system Behavior/neurological

13 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



increased basophil cell number	2 supporting datasets	Brix1^{tm1b(KOMP)Mbp}	heterozygote	Early adult	8.68x10^-45
increased eosinophil cell number	2 supporting datasets	Brix1^{tm1b(KOMP)Mbp}	heterozygote	Early adult	2.7x10^-29
increased startle reflex	1 supporting dataset	Brix1^{tm1b(KOMP)Mbp}	heterozygote	Early adult	8.59x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Brix1.

Associated images

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Histopathology

There is no histopathology data found for Brix1.

IMPC related publications

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External links

No external links available for Brix1.

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*Brix1^{tm1a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Brix1^{tm1b(KOMP)Mbp}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Brix1^{tm1e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell
*Brix1^{tm2a(KOMP)Mbp}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Brix1^{tm2e(KOMP)Mbp}*	Targeted, non-conditional allele	‌	ES Cell

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