Sfr1 | SWI5 dependent recombination repair 1
Physiological systems
22 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Embryo Growth/size/body region Nervous system Mortality/aging
17 No significant impact
2 Not tested
Data collections
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
increased circulating aspartate transaminase level | 1 supporting dataset | Sfr1em1(IMPC)Mbp | heterozygote | Early adult | 1.67x10-7 | ||
abnormal somite shape | 1 supporting dataset | Sfr1em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
preweaning lethality, complete penetrance | 3 supporting datasets | Sfr1em1(IMPC)Mbp | homozygote | Early adult | N/A * | ||
abnormal neural tube morphology | 1 supporting dataset | Sfr1em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
abnormal embryo size | 1 supporting dataset | Sfr1em1(IMPC)Mbp | homozygote | E9.5 | N/A * | ||
embryonic growth retardation | 1 supporting dataset | Sfr1em1(IMPC)Mbp | homozygote | E9.5 | N/A * |
| | | | | | | | | |
External links
No external links available for Sfr1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Sfr1em1(IMPC)Mbp | Exon Deletion | | mouse |
Sfr1tm119361(L1L2_Pgk_P) | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector |
Sfr1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
Sfr1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |