Luc7l3 | LUC7-like 3 (S. cerevisiae)

GeneMGI:1914934Synonyms: 3300001P08Rik

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Hematopoietic system Behavior/neurological Mortality/aging

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased grip strength3 supporting datasetsLuc7l3em1(IMPC)JheterozygoteEarly adult1.35x10-5 
increased erythrocyte cell number1 supporting datasetLuc7l3em1(IMPC)JheterozygoteEarly adult7.81x10-5 
embryonic lethality prior to organogenesis1 supporting datasetLuc7l3em1(IMPC)JhomozygoteE9.5N/A * 
increased circulating alanine transaminase level1 supporting datasetLuc7l3em1(IMPC)JheterozygoteEarly adult5.24x10-8 
preweaning lethality, complete penetrance1 supporting datasetLuc7l3em1(IMPC)JhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Luc7l3em1(IMPC)JExon Deletionmouse
Luc7l3tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Luc7l3tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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